News and Publications


Superbugs: Improving Citywide Surveillance and Our Understanding of Microbes
Columbia Medicine Magazine

Columbia Expands Its Microbiome Research
CUIMC Newsroom

“Superbug” MRSA Bacteria Spread in Homes
CUIMC Newsroom

Selected publications


Giddins MJ, Macesic N, Annavajhala MK, Stump S, Khan S, McConville TH, Mehta M, Gomez-Simmonds A, Uhlemann AC. Successive Emergence of Ceftazidime-Avibactam Resistance through Distinct Genomic Adaptations in blaKPC-2-Harboring Klebsiella pneumoniae Sequence Type 307 Isolates. Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e02101-17. doi: 10.1128/AAC.02101-17.


Macesic N, Green D, Wang Z, Sullivan SB, Shim K, Park S, Whittier S, Furuya EY, Gomez-Simmonds A, Uhlemann AC. Detection of mcr-1-carrying Escherichia coli causing bloodstream infection in a New York City hospital: Avian origins, human concerns? Open Forum Infect Dis. 2017 May 20;4(3):ofx115. doi: 10.1093.

Sullivan SB, Austin ED, Stump S, Mathema B, Whittier S, Lowy FD, Uhlemann AC. Reduced vancomycin susceptibility of methicillin-susceptible Staphylococcus aureus has no significant impact on mortality but results in an increase in complicated infection. Antimicrob Agents Chemother. 2017; 61(7). pii: e00316-17.

Trivedi S, Uhlemann AC, Herman-Bausier P, Sullivan SB, Sowash MG, Flores E, Khan S, Dufrêne YF, Lowy FD. The Surface Protein SdrF mediates Staphylococcus epidermidis adherence to keratin. J Infect Dis. 2017 May 8. doi: 10.1093/infdis/jix213. In press.

Gomez-Simmonds A, Uhlemann AC. Clinical implications of genomic adaptation and evolution of carbapenem-resistant Klebsiella pneumoniae. J Infect Dis 2017; 15(suppl_1):S18-S27.

Cheng L, Nelson BC, Mehta M, Seval N, Park S, Giddins MJ, Shi Q, Whittier S, Gomez-Simmonds A, Uhlemann AC. Piperacillin-Tazobactam versus Other Antibacterial Agents for Treatment of Bloodstream Infections Due to AmpC β-Lactamase-Producing Enterobacteriaceae. Antimicrob Agents Chemother. 2017; 61(6). pii: e00276-17.

Uhlemann AC, McAdam PR, Sullivan SB, Knox JR, Khiabanian H, Rabadan R, Davies PR, Fitzgerald JR, Lowy FD. Evolutionary Dynamics of Pandemic Methicillin-Sensitive Staphylococcus aureus ST398 and Its International Spread via Routes of Human Migration. mBio 2017; e01375016.


Sullivan SB, Kamath S, McConville TH, Gray BT, Lowy FD, Gordon PG, Uhlemann AC. Staphylococcus epidermidis protection against Staphylococcus aureus colonization in people living with Human Immunodeficiency Virus in an inner-city outpatient population: A cross-sectional study. Open J Inf Dis 2016; 3(4):ofw234.

Ahn D, Peñaloza H, Wang Z, Wickersham M, Parker D, Patel P, Koller A, Chen EI, Bueno SM, Uhlemann AC1,*, Prince A1. Acquired resistance to innate immune clearance promotes Klebsiella pneumoniae ST258 pulmonary infection. J Clin Invest Insight 2016; e89704.

Austin ED, Sullivan SB, Whittier S, Lowy FD, Uhlemann AC. Peripheral intra-venous catheter placement is an under-recognized source of Staphylococcus aureus bloodstream infection.Open J Inf Dis 2016; 3(2):ofw072.

Arora S, Uhlemann AC, Lowy FD, Hook M. A novel MSCRAMM sub-family in coagulase negative staphylococcal species. Frontiers Microbiol 2016; 7:540.

Gomez-Simmonds A, Hu Y, Sullivan SB, Wang Z, Whittier S, Uhlemann AC. Evidence from a New York City hospital of rising incidence of genetically diverse carbapenem-resistant Enterobacter cloacae and dominance of ST171, 2007 – 2014. J Antimicrob Chemother 2016; 71(8):2351-3.

Vega MI, Dhingra SK, Henrich PP, Straimer J, Gnadig N, Uhlemann AC, Martin RE, Lehane AM, Fidock DA. Globally prevelent PfMDR1 mutations modulate Plasmodium falciparumsusceptibility to artemisinin-based combination therapies. Nat Comm 2016; 7:11553.

Knox JR, Sullivan SB, Urena J, Miller M, Vavagiakis P, Shi Q, Uhlemann AC, Lowy FD. Environmental contamination in the home and risk of recurrent Community-Associated Methicillin-Resistant Staphylococcus aureus JAMA Int Med 2016; 176(6):807-

Reviews and Commentaries

Pereira MR, Uhlemann AC. The widening threat of carbapenem-resistant infections after liver transplantation: the case of Acinetobacter baumannii. Liver Transpl 2016; 22(5):579-81.


Laabei M, Uhlemann AC, Lowy FD, Austin ED, Yokoyama M, Ouadi K, Feil E, Thorpe HA, Williams B, Perkins M, Peacock SJ, Clarke SR, Dordel J, Holden M, Votintseva AA, Bowden R, Crook DW, Young BC, Wilson DJ, Recker M, Massey RC. Evolutionary trade-offs underlie the multi-faceted virulence of Staphylococcus aureus. PLoS Biol 2015; 13(9):e1002229.

Pereira MR, Scully BF, Pouch SM, Uhlemann AC, Goudie S, Emond JE, Verna EC. Risk factors and outcomes of carbapenem-resistant Klebsiella pneumoniae infections in liver transplant recipients. Liver Transpl 2015; 21(12):1511-9.

Gomez-Simmonds A, Greenman M, Sullivan SB, Tanner JP, Sowash MG, Whittier S, Uhlemann AC. Population structure of Klebsiella pneumoniae causing bloodstream infections at a New York City tertiary care hospital: diversification of multidrug-resistant isolates. J Clin Microbiol 2015; 53(7):2060-7.

Knox J, Van Rijen M, Uhlemann AC, Miller M, Hafer C, Vavagiakis P, Shi Q, Johnson PD, Coombs G, Kluytmans-Van Den Bergh M, Kluytmans J, Bennett CM, Lowy FD. Community-associated methicillin-resistant Staphylococcus aureus transmission in households of infected cases: a pooled analysis of primary data from three studies across international settings. Epidemiol Infect 2015; 143(2):354-65.


Benson MA, Ohneck EA, Ryan C, Alonzo F 3rd, Smith H, Narechania A, Kolokotronis SO, Satola SW, Uhlemann AC, Sebra R, Deikus G, Shopsin B, Planet PJ, Torres VJ. Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element. Mol Microbiol 2014; 93(4):664-81.

Tanner J, Lin Y, Kornblum J, Herzig CT, Bystritsky R, Uhlemann AC, Lowy FD. Molecular characterization of methicillin-resistant Staphylococcus aureus clinical isolates obtained from the Rikers Island Jail System from 2009 to 2013. J Clin Microbiol. 2014; 52(8):3091-4.

Uhlemann AC1, Dordel J1, Knox JR, Raven K, Parkhill J, Holden MT, Peacock SJ, Lowy FD. Molecular tracing of the emergence, diversification and transmission of aureus sequence type 8/USA300 in a New York community. Proc Natl Acad Sci U S A 2014; 111(18):6738-43.

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