Jennifer Lillian Small-Saunders, MD, PHD

Specialties:
Infectious Disease

Overview

Academic Appointments

  • Assistant Professor of Medicine

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center

Gender

  • Female

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Location(s)

180 Fort Washington Avenue
Floor 6
New York, NY 10032
Phone:

Insurance Accepted

Aetna

  • Aetna Signature Administrators
  • EPO
  • HMO
  • Medicare Managed Care
  • NYP Employee Plan
  • NY Signature
  • POS
  • PPO
  • Student Health

Affinity Health Plan

  • Essential Plan
  • Medicaid Managed Care

AgeWell

  • Medicare Managed Care
  • Special Needs

Amida Care

  • Special Needs

Cigna

  • EPO
  • Great West (National)
  • HMO
  • POS
  • PPO

Emblem/GHI

  • Medicare Managed Care
  • PPO

Emblem/HIP

  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Empire Blue Cross/Blue Shield

  • EPO
  • HMO
  • Medicare Managed Care
  • PPO

Empire Blue Cross Blue Shield HealthPlus

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care

Fidelis Care

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care
  • Medicare Managed Care

Healthfirst

  • Child/Family Health Plus
  • Leaf (Exchange)
  • Medicaid Managed Care
  • Medicare Managed Care

Local 1199

  • Local 1199

MagnaCare (National)

  • MagnaCare

Medicare

  • Railroad
  • Traditional Medicare

Multiplan

  • Multiplan

MVP Health Care

  • Child/Family Health Plus
  • Essential Plan
  • HMO
  • Medicaid Managed Care

Oxford Health Plans

  • Freedom
  • Liberty

RiverSpring

  • Special Needs

UnitedHealthcare

  • Compass (Exchange)
  • Empire Plan
  • HMO
  • Medicaid (Community Plan)
  • Medicare Managed Care
  • POS
  • PPO

VNSNY CHOICE

  • Medicare Managed Care
  • SelectHealth
  • Special Needs

WellCare

  • Medicaid Managed Care
  • Medicare Managed Care

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Research

Dr. Jennifer Small-Saunders is an Assistant Professor of Medicine in the Division of Infectious Diseases at Columbia University Medical Center. Her research focuses on understanding mechanisms of drug resistance in the malaria parasite, Plasmodium falciparum. Her main focus is understanding the role of tRNA modification reprogramming in artemisinin resistance.  Dr. Small-Saunders also studies the role of PfCRT in piperaquine resistance in novel haplotypes from Southeast Asia and China and modes of resistance to novel antimalarials, including nucleoside transporter inhibitors.  

Selected Publications

  1. Small-Saunders JL, Hagenah LM, Wicht KJ, Dhingra SK, Deni I, Kim J, Vendome J, Gil-Iturbe E, Roepe PD, Mehta M, Mancia F, Quick M, Eppstein MJ, Fidock DA. Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance. Plos Pathogens. 2022 Feb 7 18 (2).  PMID: 35130315
  2. Anderson MR, Geleris J, Anderson DR, Zucker J, Nobel YR, Freedberg D, Small-Saunders J, Rajagopalan KN, Greendyk R, Chae SR, Natarajan K, Roh D, Edwin E, Gallagher D, Podolanczuk A, Barr RG, Ferrante AW, Baldwin MR. Body Mass Index and Risk for Intubation or Death in SARS-CoV-2 Infection: A Retrospective Cohort Study. Ann Intern Med2020 Jul 29;doi: 10.7326/M20-3214.  PubMed PMID: 32726151; PubMed Central PMCID: PMC7397550.
  3. Small-Saunders JL, Hagenah LM, Fidock DA. Turning the tide: targeting PfCRT to combat drug-resistant P. falciparum?. Nat Rev Microbiol2020 May;18(5):261-262doi: 10.1038/s41579-020-0353-8. PubMed PMID: 32300249; PubMed Central PMCID: PMC7269106.
  4. Dhingra SK, Small-Saunders JL, Ménard D, Fidock DA. Plasmodium falciparum resistance to piperaquine driven by PfCRT. Lancet Infect Dis2019 Nov;19(11):1168-1169doi: 10.1016/S1473-3099(19)30543-2. PubMed PMID: 31657776; PubMed Central PMCID: PMC6943240.
  5. McLean KJ, Straimer J, Hopp CS, Vega-Rodriguez J, Small-Saunders JL, Kanatani S, Tripathi A, Mlambo G, Dumoulin PC, Harris CT, Tong X, Shears MJ, Ankarklev J, Kafsack BFC, Fidock DA, Sinnis P. Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters. Sci Rep2019 Sep 11;9(1):13131doi: 10.1038/s41598-019-49348-x. PubMed PMID: 31511546; PubMed Central PMCID: PMC6739413.
  6. Dhingra SK, Gabryszewski SJ, Small-Saunders JL, Yeo T, Henrich PP, Mok S, Fidock DA. Global Spread of Mutant PfCRT and Its Pleiotropic Impact on Plasmodium falciparum Multidrug Resistance and Fitness. mBio2019 Apr 30;10(2)doi: 10.1128/mBio.02731-18. PubMed PMID: 31040246; PubMed Central PMCID: PMC6495381.
  7. Zhao N, Darby CM, Small J, Bachovchin DA, Jiang X, Burns-Huang KE, Botella H, Ehrt S, Boger DL, Anderson ED, Cravatt BF, Speers AE, Fernandez-Vega V, Hodder PS, Eberhart C, Rosen H, Spicer TP, Nathan CF. Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis. ACS Chem Biol2015 Feb 20;10(2):364-71doi: 10.1021/cb500746z. Epub 2014 Dec 5. PubMed PMID: 25457457; PubMed Central PMCID: PMC4340348.
  8. Small JL, Park SW, Kana BD, Ioerger TR, Sacchettini JC, Ehrt S. Perturbation of cytochrome c maturation reveals adaptability of the respiratory chain in Mycobacterium tuberculosis. mBio2013 Sep 17;4(5):e00475-13doi: 10.1128/mBio.00475-13. PubMed PMID: 24045640; PubMed Central PMCID: PMC3781833.
  9. Small JL, O'Donoghue AJ, Boritsch EC, Tsodikov OV, Knudsen GM, Vandal O, Craik CS, Ehrt S. Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis. J Biol Chem2013 May 3;288(18):12489-99doi: 10.1074/jbc.M113.456541. Epub 2013 Mar 15. PubMed PMID: 23504313; PubMed Central PMCID: PMC3642297.
  10. Biswas T, Small J, Vandal O, Odaira T, Deng H, Ehrt S, Tsodikov OV. Structural insight into serine protease Rv3671c that Protects M. tuberculosis from oxidative and acidic stress. Structure2010 Oct 13;18(10):1353-63doi: 10.1016/j.str.2010.06.017. PubMed PMID: 20947023; PubMed Central PMCID: PMC2955984.